BBC Inside Science Folgen

T-Cells in vaccinated people may be holding the fort, or at least fighting serious illness, against the latest SARS CoV2 variant. Also, how the briefest of sleeps aids creativity.Prof Penny Moore, of South Africa’s National Centre for Infectious Disease and Witwatersrand University in Johannesburg, joins us again this week to give us an update from the front line of scientists trying to get the data we need to try to predict the seriousness of the omicron variant. These early data, published as pre-prints and not yet peer-reviewed, seem to suggest that for those in the world lucky enough to have "seen a spike" three times (double vaccination plus booster, or double vaccination plus recovered from infection) the chances of serious illness remain similar to earlier variants.One chink of hope continues to be the fascinating response of the "killer" T-Cells. Prof Danny Altmann of Imperial College London attempts to give us a T-Cell 101 course. This other division of the body’s defences, besides the binding antibodies of which we hear so much, may be more resilient to the sorts of mutations the virus has shown so far, and also perhaps have a slower waning in their ability to recognize it at all.What did Salvador Dali and Thomas Edison have in common? A fondness for the occasional creative nap. And this week scientists suggest they weren't wrong.Delphine Oudiette, a sleep researcher at the L’Institut du Cerveau et de la Moelle épinière in Paris, has been experimenting with the idea that just a small nap, where you doze off for a few seconds but don't fall into deep sleep statistically helps you solve creative or mathematical problems. Her results are published in the journal Science Advances. Meanwhile, in shallow seas off Indonesia, attempts to regrow coral reefs previously pounded to rubble by fishing with explosives, really sound like they are recovering. How do scientists know? By swimming about with microphones of course. Dr Tim Lamont, a marine Biologist at the University of Exeter has been listening to thousands of recordings of fish and other marine animal noises and talks Vic through some of the odder ones that so far can't be recognized. He says the sheer number and frequency of the odd sounds point to an ecosystem beginning to thrive. The coral rebuilding strategy there won't work for all the world's dwindling corals, but this new way of monitoring success or failure makes for a great listen.Presenter: Victoria Gill Producer: Alex Mansfield Assistant Producer: Emily BirdMade in Association with The Open University

As virologists around the world race to investigate the latest SARS CoV2 variant of concern, the UN’s World AIDS Day this week reminds us of the other global pandemic raging for some 40 years. Much of the work achieved over the last two years on SARS CoV2 has been achieved because of the investment made into, and the understanding gained from, HIV research over the last two decades. But to what further extent do they overlap in the population? There is a theory that the omicron variant, displaying so very many mutations compared to previous variants, might well have been incubated in a person suffering from a compromised immune system, possibly due to HIV, in whom the covid virus was able to linger longer than in fitter individuals. Prof. Penny Moore, of South Africa’s National Centre for Infectious Disease and Witwatersrand University in Johannesburg, is one of many virologists who transferred from HIV to coronavirus research, and hers, like hundreds of labs around the world, is racing to clone the parts of the omicron virus to enable research into its transmissibility and severity as soon as possible. She describes to Vic what we yet know and what we don’t about it, and also how it is high time to bring the same sense of urgency back to HIV research.Nottingham University’s Prof. Jonathan Ball is another virologist who suddenly transferred experience over to coronaviruses early on. He outlines something of what is really happening when viruses mutate, and how the arms race between host and invader can play out. Our regular Inside Science listener will be interested to know that this week Merlin Sheldrake was awarded the Royal Society’s Science Book Prize, sponsored by Insight Investment, and the hefty cheque that accompanies it, for his book Entangled Life: How Fungi Make Our Worlds, Change Our Minds and Shape Our Futures. Merlin is one of several high profile advisors to something called the Society for the Protection of Underground Networks - SPUN. They have received funding recently to begin an international mission to map the world’s subterranean fungal mycelial networks, including the infamous Wood Wide Web. SPUN Co-Founder Prof. Toby Kiers of VU University in Amsterdam tells Vic about the need to preserve, map and cherish this unseen yet essential part of the global ecosystem.And could rising sea levels paradoxically be used to help fight climate change? Researchers up in St Andrews took Vic for a squelch about the salt marshes reclaimed recently by the sea in an estuary near Grangemouth, where flora and fauna are thriving just a few years since the seas were allowed back in. Finally, you may have thought that wasps eat meat whereas bees eat honey and nectar. But this week we learned that some bees eat meat, preserving it in honeycombs to feed young and augment their own nutrition. Intrepid field entomologist Laura Figueroa of Cornell University describes to Vic her work in the jungle with Vulture Bees, social bees that over evolutionary time seem to have rescinded their vegetarian instincts and now are happy to enjoy a bit of “chicken on the side”. Laura found that they can digest their flesh because of big adjustments to their gut microbes, including acid-loving bacteria also found in other carnivorous animals. Presented by Victoria Gill Produced by Alex Mansfield Assistant Producer, Emily Bird Made in Association with The Open University

Malaria, a disease that infects hundreds of millions of people and kills hundreds of thousands each year. It is caused after a plasmodium parasite is passed from a blood-feeding mosquito into a human host. Subject to much research over hundreds of years, of both host and parasite, one of the evolutionary mysteries has been why the plasmodium so prospers in the mosquito populations in infected areas. Why haven’t mosquitoes’ immune systems learned to fight back for example? In short, what’s in it for the mozzies? Ann Carr, working with Laurence Zwiebel at Vanderbuilt University, reports in the journal Nature Scientific Reports how they managed to discover a mutual symbiotic relationship between the plasmodium and the mosquito. Using advanced sequencing technology they discovered that the infected insects can live longer, and have enhanced sensing (olfaction) and egg positioning than their uninfected brethren. This, in turn, could help them finds meals better, bestowing higher numbers of infection opportunities for the parasite, and benefitting both.NASA this week successfully launched its DART mission, which will next year attempt to nudge an asteroid in its orbit by smashing a mass into it. Could this method allow future humans, endangered by an impending collision push an asteroid out of the way to save the planet? It is billed as human’s first ever “earth-defence mission”, but as relieved-sounding mission leads Nancy Chabot and Andy Rivkin of Johns Hopkins University told the BBC, it is perhaps finally time to stop talking about these sorts of things and have a go.Less relieved perhaps are astronomers around the world, as the James Webb Space Telescope team announce a further small delay to its launch to sometime after December 22nd. The BBC’s John Amos a few weeks ago stood in the presence of the telescope before it was coupled to the launch vehicle, and spoke with ESA’s Peter Jensen about its cost and complexity. BBC Inside Science is planning a special episode devoted to the instrument to accompany the launch of this successor to the Hubble Space Telescope. Watch, as they say, this space...And finally an insight perhaps into the origin of words and language. Apart from onomatopoeia, where a word can sound like the noise of a noise-making thing, can a word sound like other properties, such as for example its shape? In the late 1920s psychologists found that different people would match certain made-up words with the same abstract shapes. This “Bouba/ Kiki” effect has been studied since, where the word “Bouba” is associated with rounded blobby shapes, and “Kiki” with spikier, angular forms.But there wasn’t so much evidence whether or not the effect worked across different languages or different written alphabets, until now.Aleksandra Ćwiek of Leibniz-Zentrum Allgemeine Sprachwissenschaft in Berlin tells Gaia of her international study (published in Royal Society Phil. Trans. B) looking at the effect in 25 different languages and cultures. The effect is robust across the different writing systems and locations, so the link is not simply about the shape of a letter b or letter k when written in a latinate alphabet, but could allude to something much deeper.Presented by Gaia Vince Produced by Alex Mansfield Assistant Producer, Emily BirdMade in Association with The Open University.