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BBC Inside Science

A weekly programme that illuminates the mysteries and challenges the controversies behind the science that's changing our world.

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566 Folgen
  • Folge vom 25.06.2020
    The Human Genome Project's 20th Anniversary
    Adam Rutherford is back to celebrate the 20th anniversary of one of the most ambitious and revolutionary scientific endeavours of all time - the Human Genome Project. Its scope and scale was breath-taking, set up to read every one of the 3 billion nucleotides, or letters of genetic information, contained within the DNA in every cell of the human body. It took seven years, hundreds of scientists, cost almost $3 billion and, amazingly, came in under budget and on time. Adam reflects back on that momentous time with Ewan Birney, Director of the European Bio-informatics Institute, part of the European Molecular Biology Laboratory. Twenty years ago, he was a PhD student working on the project, in the months leading up to the first draft. The Human Genome Project underpins many branches of science, from human evolution and synthetic biology to forensic genetics and ancestry testing. But a key motivation for the project was to alleviate human suffering. While the ‘cures’, hyped by the media back in 2000, were not realistic our understanding of disease has been revolutionised. Adam talks to Cancer Research UK Scientist, Dr Serena Nik-Zainal, from Cambridge University, who explains why the sequencing of the human genome has been so crucial to the diagnosis and treatment of breast cancer. The Human Genome Project is also playing a crucial role in the COVID-19 pandemic. Dr Kenneth Baillie has been treating critically ill patients at Edinburgh’s Royal Infirmary since the pandemic started. As the Lead on GenOMICC, a global collaboration on genetics and critical illness, he has joined forces with Genomics England and the NHS, to pinpoint genetic signals in these patients to help identify the best treatments.Producers: Beth Eastwood & Fiona Roberts
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  • Folge vom 18.06.2020
    Coronavirus conspiracy, Listeners' mask questions, Solar Orbiter gets close to the Sun
    Throughout the pandemic, we've seen an explosion in information about the science of the virus, SARS-CoV-2, and the disease it causes, COVID-19. An article online, or a text forwarded, could be true and sounds about right, but how do you know that it's accurate? When scrolling through your social feed, how do you decipher fact from fiction? A new report, by Kings College London and Ipsos MORI, reveals that those of us who get our news from social media are more likely to believe misinformation about the pandemic.Marnie talks to Jack Goodman of the Anti-Disinformation Unit at BBC Online, a new team set up to tackle the problem. She finds out how science fact turns to science fiction online, and what the team is doing to try to counter this.Now that wearing face masks are now mandatory in a number of situations, a lot of us are making our own. BBC Inside Science listeners sent in lots of ideas about the design, maintenance and durability of face masks, and other ways to protect against spreading the coronavirus. We asked Professor of Materials & Society at UCL Mark Miodownik in to comment.In February this year, the European Space Agency’s Solar Orbiter, SolO, successfully launched, escaping this planet before most of us went into lock-down. Professor Lucie Green from the Mullard Space Science Lab at University College London, is a solar scientist and part of the team that will be using a telescope to take images of the Sun in extreme ultraviolet light. The orbiter is now in it’s ‘Cruise Phase’ which means most of its instruments have now been tested and calibrated, but aren’t yet up and running. One instrument that has been operational since just after launch is the magnetometer, which will collect data on the Sun’s complex and dynamic magnetic field.Presenter - Marnie Chesterton Producers - Fiona Roberts and Beth Eastwood
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  • Folge vom 11.06.2020
    Engineering out of lockdown and should we castrate male dogs?
    As the UK gradually begins to ease out of lockdown, Marnie explores how engineers are hoping to reduce the spread of Covid-19. We’ve learned how infected people exhale droplets and aerosols, containing the virus, and how we can then either inhale them, or transfer them to our faces by touching contaminated surfaces. Many shops already have screens and physical barriers, while schools and offices are re-configuring desks and walkways. What role does the environment play in our overall risk of becoming infected and what can we do about it? This is the focus of the SAGE Environmental Working Group. Marnie talks to its Chair, Catherine Noakes, Professor of Environmental Engineering for Buildings at Leeds University. Minimising the risks that contaminated surfaces pose is a key challenge that engineers are now trying to address. Marnie asks Birmingham University Research Scientist, Felicity de Cogan, about the surface she created which kills bacteria in seconds. She's now re-purposing the technology to kill the virus that causes Covid-19. If her laboratory studies prove that it kills the virus as quickly, as she hopes, the technology could be used to create antiviral PPE that can be re-used rather than thrown away.Epidemiology has been thrust into the spotlight in recent months, helping us track the viral threat facing all of us. But companion animal epidemiology - which studies disease in pet populations - is a much younger field. It’s one that’s starting to search for the answers to another puppy-related conundrum that’s been puzzling BBC Inside Science reporter Geoff Marsh - should he get puppy Kevin castrated? Neutering has become a cultural norm in the UK. But the health risks to neutered male dogs include cancers and joint disorders in some breeds. The operation and anaesthetic carries some risk as does the age of the dog when the operation is carried out. The risk of dog populations exploding with hundreds of un-neutered dogs is low, because most owners control their dogs to such a degree the chance of unplanned mating doesn't come up. But neutering can help with some behavioural problems in pet dogs. So what is the answer? Will Kevin remain intact?Presenter - Marnie Chesterton Producers - Beth Eastwood and Fiona Roberts
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  • Folge vom 04.06.2020
    Back to School and Covid-19 and Ordnance Survey and the pandemic
    As the lockdown eases and some children, in preschool and primary years, start heading back to school, what impact will this have on the pandemic, how will we know and is there anything we can do about it? Marnie Chesterton talks to Professor of Mathematical Biology at Cambridge University, Julia Gog, who co-chaired the group that advised the government on the impact of easing school closures. She explains why the limited opening of schools provides a golden opportunity to learn about its impact on the pandemic, and inform what happens in September when the new school year begins. Marnie also talks to Tim Spector, Professor of Genetic Epidemiology at King’s College London, to find out what parents can do to help control the spread of the virus in their communities. He runs the COVID Symptom Study, a huge citizen science project that’s pinpointing the symptoms most closely associated with Covid-19. Millions of British adults have downloaded the app, to take part in the study, logging how they feel each day and adding symptoms when they feel unwell. The breakthrough that losing your sense of smell, or anosmia, is a common symptom in Covid-19, arose from this app. While children with Covid-19 tend to have mild or no symptoms, Tim Spector believes that some cases are being missed because many of the symptoms we’re told to look out for in adults, such as fever, are transient or absent in children. Tim explains which symptoms parents should look out for in children, including anosmia and a range of rashes such as ‘covid toe’. If parents log their children’s symptoms each day, the hope is he’ll have enough data to further refine the symptoms most closely associated with Covid-19 in children. Parents will then be better placed to spot them, if they occur, and keep their children at home.You might be forgiven for thinking that Ordnance Survey (OS), the national mapping agency for Great Britain, would be having a quiet time during the lockdown. But its online OS Map apps have seen a 300% increase in use, with users not only checking out new places and walks in their local area, but using the virtual maps to plan and imagine themselves on walks in more remote and far flung parts of Great Britain. But Ordnance Survey is so much more than just leisure maps. It runs the Master Map of Great Britain, a massive, interactive, geospatial database which can be interrogated by anyone in the public sector with questions on geography, planning, logistics, addresses and more. The list is long. And during the coronavirus pandemic, the Mapping for Emergencies service has been busy helping the NHS find places for blood testing facilities and PPE storage; working out which walkways are wide enough to allow social distancing, working out where the nearest pharmacies to vulnerable people are and much more. Presenter - Marnie Chesterton Producers - Beth Eastwood and Fiona Roberts
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