BBC Inside Science Folgen

A year after the first SARS-Cov2 sequences were received in the vaccine labs, Dr Alex Lathbridge and guests look into ongoing development and what next year's booster shots might be like. Prof Robin Shattock's team at Imperial College are still working on their vaccine technology - called 'Self Amplifying RNA' or saRNA. A little bit behind their well financed corporate colleagues, this week they announced that instead of pressing ahead with a phase III trial, they will instead look to developing possible boosters and alternative targets just in case more and more serious mutations happen. But as Prof Anna Blakney explains from her lab at University of British Columbia, the possibilities of saRNA don't stop with coronaviruses.Researchers in the journal PNAS report this week a new theory as to when and where dogs were first domesticated by humans, and suggest that they accompanied the first humans across the Bering straight into America. Inside Science's Geoff Marsh has a sniff around.And Dr Dean D'Souza from Anglia Ruskin University describes in Science Advances work he has done looking at certain kinds of development in children who grow up in bilingual households. His work suggests a slightly faster and keener observation of detailed changes in visual cues, and that this seems to be a trait that survives into adulthood. Presented by Alex LathbridgeProduced by Alex MansfieldMade in Association with The Open University

Reports this week talk of some BAME ethnic minorities being significantly less likely to take a covid vaccine if offered. Vittal Katikireddi and Tolullah Oni both sit on the SAGE ethnicity subgroup, and they discuss with Alex Lathbridge where the figures come from and quite what they might mean. Some of these same groups have suffered some of the worst outcomes from infection. Addressing any underlying problems that bely the figures will take a nuanced approach.Researchers in Japan and Liverpool have been investigating cat's prediliction for the herbs Catnip and Silver Vine. It turns out that there may well be a deep evolutionary reason they have evolved to love rubbing it in their fur so much: a key ingredient is a good mosquito repellent. As Professors Masao Miyazaki and Jane Hurst describe. It could help keep the mozzies away but you might end up being tailed by cats.And researcher Iestyn Woolway of the European Space Agency Climate Group, at Didcot UK, describes his work modelling the world's lakes' reaction to a warming climate over coming decades. It's not very comforting, with increased duration and intensity of what he calls "Lake Heatwaves".Presented by Alex Lathbridge Produced by Alex MansfieldMade in associataion with the Open University.Note: This podcast has been edited since the original broadcast to prevent any possible inference that the Tuskegee syphilis study involved the deliberate infection of subjects. In the Tuskegee study, African American patients who were already infected with syphilis had diagnosis and treatment deliberately withheld from them in order to observe the progression of the lethal disease over several decades (even after a perfectly simple treatment - penicillin - became available).

In the new EU-UK deal, the UK is to be an associate member of the latest EU research funding round, known as Horizon Europe. Costing around £2bn to take part, what can UK scientists now do and what has changed? UKRI CEO Otteline Leyser and the Wellcome Trust EU specialist Beth Thompson discuss ways in which UK researchers are breathing a sigh of relief.Of all the ways the UK can now diverge from the EU, DEFRA is currently holding an open consultation on whether to tweak the current GMO regulations so as not to include CRISPR-style Genetic Editing. The EU is coincidentally looking at the same issue. John Innes Centre's Janneke Balk works on making strains of wheat that have a higher level of iron for nutritional fortification. Interim head of the Roslin Institute in Scotland Bruce Whitelaw thinks developing disease resistance in farm animals is a potentially profitable area. Both agree the GMO regulations should be more tightly specified to bring clarity and opportunity for innovation. In Iceland, Kari Stefansson's company Decode Genetics analyze the genetic codes of most of the population of Iceland. This has allowed them to look at the parents, siblings, and offspring of identical twins, and identify how early genetic differences between them develop. And it's very early indeed. Given that identical twins studies are so often used to address issues surrounding the so-called Nature-vs-Nurture debate, the findings, published in the Journal Nature, are striking. Presenter by Marnie Chesterton Produced by Alex MansfieldMade in association with the Open University.