Patients who suffer neurological impairments preventing them from speaking potentially face a severely limited existence. Being able to express yourself in real time is a large part of our identity. In the journal Nature this week, scientists from the University of California, San Francisco, report a new technique for synthesising speech based on measurements of neural signals taken from the brain. Author Dr Gopala Anumanchipalli tells Adam about how this proof of principle could one day form the basis for a speech prosthesis for patients who have lost the ability to converse. Around the world this weekend (April 26th-29th 2019) people are being encouraged to participate in the City Nature Challenge, a global effort to catalogue urban wildlife using a free mobile app. Reporter Geoff Marsh travelled to the California Academy of Sciences, home of the initiative, to meet those behind it and how we might all take part.The third act in our drama is a chat with journalist and writer Will Storr about his new book - the Science of Storytelling - which explores the structure of stories with relation to our evolution and brain structure. Primeval instincts of expectation, subversion and causation intertwine with camp-fire sagas from the beginning of conversation. What can this science of storytelling contribute to the art of telling stories about science? A ripping yarn indeed.Producer: Alex Mansfield
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BBC Inside Science Folgen
A weekly programme that illuminates the mysteries and challenges the controversies behind the science that's changing our world.
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Folge vom 25.04.2019Thought-to-speech machine, City Nature Challenge, Science of Storytelling
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Folge vom 18.04.2019Notre-Dame fire, Reviving pig brains, ExoMars, Evolution of facesThe horror of the blazing Notre-Dame cathedral in Paris has been slightly quenched by the fact that so much of the French landmark has been saved. But what was it about the structure of the roof, with some the beams dating from the 13th century, that meant it burned like a well-stacked bonfire? Guillermo Rein is Professor of Fire Science at Imperial College London , and he explains to Adam Rutherford how wood burns and how it was the intricate mixture of large and small beams, and very poor fire protection measures that made the iconic roof, so vulnerable.An experiment to see whether isolated dead pig brains could be preserved at the cellular level in order to study post mortem brains, had a surprising outcome. The BrainEx technology of perfusing the brains with chemicals that should have just halted the rapid degradation of cellular structure in the brain, that occurs soon after death, actually caused them to start firing neurons, reacting to drugs and generally behaving as if they were alive. Although, it has to be stressed, there was no whole-brain connectivity or consciousness achieved, it does raise ethical questions about death, if this method was to be developed for use in humans. Bioethicist at Kings College London, Silvia Camporesi explores the facts that reveal that death is a process rather than a single event and what this might mean for patients that are diagnosed as brain dead.Where is the Martian methane? This is the question Mannish Patel at the Open University has been left pondering after the ExoMars Trace Gas Orbiter came up empty handed in detecting the gas on Mars. Methane could be a signature of past of present life on the Red Planet, it's been measured by NASA's Curiosity rover and by telescopes on Earth, but the far more sensitive and specialised TGO has so far failed to detect the gas. It could be because methane levels in the thin Martian atmosphere is a seasonal event, we'll just have to ait for an entire Martian year of surveys to be able to solve this mystery.Our faces are incredibly important in our lives, we feed through them, they are the conduit for our sensory interaction with the universe, via smell, hearing and vision; we speak, and we convey the subtlest emotions with a raised eyebrow, a wry smile, a clenched jaw or eyes wide open. It is the central importance of these features that has meant we’ve been intensively studying the evolution of the face for decades, to work out why we look the way we do, and how much of our looks reflects adaptations that enhanced our survival, and how much is just down to quirks of evolution. Anatomist, Paul O’Higgins from York University is interested in how all that has influenced our faces. Producer: Fiona Roberts
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Folge vom 11.04.2019Visualising a black hole, Homo luzonensis, Two ways to overcome antimicrobial resistance"We have now seen the unseeable" according to scientists who are part of the Event Horizon Telescope group. The international team has released a picture of the first black hole. Data gathered from an array of over 8 radio telescopes has been crunched to create a picture of the super-hot plasma surrounding the black hole M87. It shows extremely excited photons on the brink of being swallowed up by the supermassive black hole, 500 million trillion km away. Marnie Chesterton, asks UCL cosmologist Andrew Pontzen what the glowing doughnut-shaped image can tell us about the laws of gravity and relativity.A new species of hominin has been discovered in caves at the northernmost tip of the Philippines, on the island of Luzon. The discoverers have called this creature Homo luzonensis, and it's thought to be 50,000 years or older. The teeth, hand and foot bones suggest it could have been a mixture of early modern humans - Homo sapiens- and older ancestors like the Australopithecines. Cambridge University's Leverhulme Professor of Human Evolution, Robert Foley suggests some caution with calling this a new species, and explains how populations of hominins isolated on islands could evolve to be different by a mechanism called genetic drift.The world is facing an antimicrobial crisis. The global fight against infections is looking worrying as more and more strains of bacteria emerge which are resistant to our stocks of antibiotics. Marnie visits to Tblisi, in Georgia to meet scientists who are looking at a different way to fight infections, collecting and using the microscopic phage viruses which infect the bacteria which infect us. Another way to try and beat antibiotic resistance was the focus for Susan Rosenberg at the Baylor College of Medicine in Houston Texas, when she thought it might be clever to try and stop microbes evolving resistance to antibiotics . She discovered that when microbial cells are stressed, a number of them actually start to mutate at a greater rate. This means they stand a greater chance of mutating into a form that has some resistance to our drugs. But by learning about the finer details of this mechanism, and finding a drug that can halt it. She and her team hope to skew the evolutionary arms race between microbes and antibiotics and our immune systems in our favour.Producer: Fiona Roberts
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Folge vom 04.04.2019Cretaceous catastrophe fossilised, LIGO and Virgo, Corals, Forensic shoeprint databaseAbout 66 million years ago an asteroid at least 6 miles wide crashed into the Earth, in the shallow sea that is now the Yucatan Peninsular in Mexico. It gouged the Chicxulub crater 18 miles deep; threw 25 trillion tonnes of debris into the atmosphere, much of which was hotter than the Sun, created huge seismic waves and massive tsunamis churning the Gulf of Mexico, tearing up coastlines and peeling up 100’s of metres of rock. 75% of the Earth’s forest burned. Debris was thrown out across the Solar System and North America was showered by a fan of glassy molten rock droplets. This geological event marked the end of the Cretaceous period and the start of the Palaeogene. Most people accept that this massive event caused the last great extinction, the end of the dinosaurs and a period of intense cold. Many fossil finds back this theory up. But very little fossil evidence showing the impact of the actual event has been found. Until now. Hundreds of miles from Chicxulub in a fossil site called Tanis, in North Dakota, part of the vast Hell Creek formation, is a fossil find that depicts the turmoil 10's of minutes after the asteroid hit. Marine and freshwater fish are found tangled together with these glassy droplets crammed in their gills, Charred trees are mixed up with hundreds of mangled animal bones, amber perfectly preserving drops of what was molten Earth. It's got palaeontologists including Professor Phil Manning at Manchester University very excited.The gravitational wave detectors LIGO and VIRGO have been recently upgraded and made more sensitive to the miniscule signals that denote ripples in gravity - gravitational waves. Professor Sheila Rowan of the University of Glasgow explains to Gareth Mitchell that she hopes that with this third run of the detectors, they will be finding not just one or two signals that provide evidence of massive events in our universe, but hundreds, maybe even thousands.In the quest to understand how corals are affected by rising sea temperatures we need to understand the symbiotic relationship they have with dinoflagellates, the single-celled algae that live in, and use photosynthesis to make food for the coral. When coral gets too hot and undergoes 'bleaching', this is the algae leaving the coral. Yixian Zheng at the Carnegie Institution of Washington takes Roland Pease on a tour of her coral tanks and explains that she's hunting for a model coral organism to study this process at the genetic and molecular level.A crime has been committed in the studio. Gareth's tea has been drunk and his biscuits have been nibbled. Luckily evidence was left at the scene of the crime - a shoeprint with distinctive wear patterns. One quick phone call and the director of the Leverhulme Research Centre for Forensic Science at the University of Dundee, Professor Niamh Nic Daeid is on the case. She's asking the public to help build up a database of footwear prints. The project is the largest ever study into the variation in footwear marks made by the same shoes across different surfaces and activities so that the variation observed can be used to explore links between the shoe and the mark it makes. In order to do this, she's asking thousands of individuals to take part in a large-scale citizen science project by taking pictures of their footwear and the marks they make. This will help the Dundee team build a substantial database for use in their research to aid the scientific validation of footwear marks as evidence for use in the criminal justice system.Producer (and biscuit thief) - Fiona Roberts