File on 4 Investigates Folgen

Dutch and American scientists have succeeded in mutating a deadly bird-flu virus to make it easily transmissible to humans. If it got out, it could start a fatal epidemic. They keep it securely locked away in their laboratories, but want to publish the biological recipe for making it. In an unprecedented move, the U.S. government is pressing them to keep the details of their experiments secret for fear that bio-terrorists could use the organism to kill hundreds of millions of people. In the UK there are more than 300 laboratories working on the second highest danger level organisms such as tuberculosis. In 10 of them, they work at the highest risk level on viruses like ebola and the most deadly strains of flu. Every year there are hundreds of biological related incidents reported to the Health and Safety Executive but while the headline numbers are published the details are shrouded in secrecy and rarely come to light. Meanwhile, a rapidly developing branch of science known as 'synthetic biology' offers dramatic possibilities for developing new vaccines and targeting many lethal diseases. But does it also increase the risk that newly-created organisms could be used for harmful purposes as the necessary research techniques spread out from authorised laboratories to a network of DIY enthusiasts? There is growing concern that that biological techniques are advancing so quickly that they outstrip the mechanisms to control them. The FBI has tasked a unit to monitor the DIY enthusiasts but admits it only has limited resources to do so. Could genetic mutation of pathogens become as commonplace as home-brewing? And how well protected is the UK against biological threats? Reporter : Gerry Northam Producer : Nicola Dowling Editor : David Ross.

Inquests in England are increasingly hearing a new term to explain deaths in police custody: Excited Delirium. It's a diagnosis with origins in the United States, where it has been associated with consumption of massive doses of cocaine. People with ED are said to possess super-human strength and to be largely impervious to pain. They behave bizarrely, sometimes destructively.They often seem paranoid and frequently resist arrest. As police struggle to restrain them they overheat and die. But critics -- including some British Pathologists -- point out that Excited Delirium is not recognised by the World Health Organisation and that there is a lack of valid research. Civil liberties organisations fear that the diagnosis might be employed to excuse improper use of restraint techniques by police. For 'File on 4' Angus Stickler has travelled to the cocaine capital of the United States, Miami, where police and scientists are attempting to define and deal with the controversial condition.And in England he speaks to families whose loved ones have died after being restrained by the police. Is Excited Delirium well-enough understood to be used by courts? And just how many people are dying while being restrained -- either in custody or while being arrested? Are the official figures reliable? Producer: Andy Denwood.

Jenny Cuffe talks to foster parents who find themselves battling with local authorities over the children in their care. They describe a Kafkaesque nightmare where doors are shut, telephone calls and emails unanswered, even court orders are ignored. Meanwhile, vulnerable children are treated as pawns as social workers move them from one place to another.In one case investigated by File on 4, foster parents who offered to care for four siblings were denied the financial and practical support they needed from the council. Their official complaints were upheld yet key recommendations continued to be ignored and, as a consequence, the children have now been split up. After giving up their jobs to care for the children, the couple are now in debt and have to sell their home. The local MP describes the council's treatment of the family as outrageous. He says the case is extreme but not unusual and he's called for an enquiry. In another case, a teenager with complex mental and physical needs was unlawfully removed from the foster home where he'd grown up. His sister told File on 4: "When he was in his foster mum's care he was always clean, always happy and he looked well but when I saw him he was dishevelled. It was as if someone took him away from himself. I felt his personality had gone." When his foster mother went to court to get him back, she was vilified by the council who used public funds to defend their actions to the bitter end but lost in court.A recent report identified a shortage of foster carers in the UK but are some councils driving away the people who should be their best resource?Producer: Sally Chesworth.