In Our Time: Science Folgen

Melvyn Bragg and guests discuss the life and work of Louis Pasteur (1822-1895) and his extraordinary contribution to medicine and science. It is said few people have saved more lives than Pasteur. A chemist, he showed that otherwise identical molecules could exist as 'left' and 'right-handed' versions and that molecules produced by living things were always left-handed. He proposed a germ theory to replace the idea of spontaneous generation. He discovered that microorganisms cause fermentation and disease. He began the process named after him, pasteurisation, heating liquids to 50-60 C to kill microbes. He saved the beer and wine industries in France when they were struggling with microbial contamination. He saved the French silk industry when he found a way of protecting healthy silkworm eggs from disease. He developed vaccines against anthrax and rabies and helped establish immunology. Many of his ideas were developed further after his lifetime, but one of his legacies was a charitable body, the Pasteur Institute, to continue research into infectious disease.With Andrew Mendelsohn Reader in the School of History at Queen Mary, University of LondonAnne Hardy Honorary Professor at the Centre for History in Public Health at the London School of Hygiene and Tropical Medicineand Michael Worboys Emeritus Professor in the History of Science, Technology and Medicine at the University of Manchester Producer: Simon Tillotson.

After 27 years, Melvyn Bragg has decided to step down from the In Our Time presenter’s chair. With over a thousand episodes to choose from, he has selected just six that capture the huge range and depth of the subjects he and his experts have tackled. In this fifth of his choices, we hear Melvyn Bragg and his guests discuss a key figure from quantum mechanics.Their topic is the life and ideas of Wolfgang Pauli (1900-1958), whose Exclusion Principle is one of the key ideas in quantum mechanics. A brilliant physicist, at 21 Pauli wrote a review of Einstein's theory of general relativity and that review is still a standard work of reference today. The Pauli Exclusion Principle proposes that no two electrons in an atom can be at the same time in the same state or configuration, and it helps explain a wide range of phenomena such as the electron shell structure of atoms. Pauli went on to postulate the existence of the neutrino, which was confirmed in his lifetime. Following further development of his exclusion principle, Pauli was awarded the Nobel Prize in Physics in 1945 for his 'decisive contribution through his discovery of a new law of Nature'. He also had a long correspondence with Jung, and a reputation for accidentally breaking experimental equipment which was dubbed The Pauli Effect.With Frank Close Fellow Emeritus at Exeter College, University of OxfordMichela Massimi Professor of Philosophy of Science at the University of EdinburghandGraham Farmelo Bye-Fellow of Churchill College, University of CambridgeProducer: Simon TillotsonSpanning history, religion, culture, science and philosophy, In Our Time from BBC Radio 4 is essential listening for the intellectually curious. In each episode, host Melvyn Bragg and expert guests explore the characters, events and discoveries that have shaped our world

Melvyn Bragg and guests discuss the high temperatures that marked the end of the Paleocene and start of the Eocene periods, about 50m years ago. Over c1000 years, global temperatures rose more than 5 C on average and stayed that way for c100,000 years more, with the surface of seas in the Arctic being as warm as those in the subtropics. There were widespread extinctions, changes in ocean currents, and there was much less oxygen in the sea depths. The rise has been attributed to an increase of carbon dioxide and methane in the atmosphere, though it is not yet known conclusively what the source of those gases was. One theory is that a rise in carbon dioxide, perhaps from volcanoes, warmed up the globe enough for warm water to reach the bottom of the oceans and so release methane from frozen crystals in the sea bed. The higher the temperature rose and the longer the water was warm, the more methane was released. Scientists have been studying a range of sources from this long period, from ice samples to fossils, to try to understand more about possible causes. With Dame Jane Francis Professor of Palaeoclimatology at the British Antarctic SurveyMark Maslin Professor of Palaeoclimatology at University College LondonAndTracy Aze Lecturer in Marine Micropaleontology at the University of LeedsProducer: Simon Tillotson.