A Massachusetts man who received a kidney from a genetically modified pig is recovering well. Also, on April 8, a total solar eclipse will plunge parts of North America into darkness. Scientists answer the questions you asked.Recipient Of Pig Kidney Transplant Leaves The HospitalLast month, Massachusetts General Hospital in Boston announced that a team of doctors had transplanted a kidney from a genetically engineered pig into a living human for the first time. This week, that patient, a 62-year-old man living with end-stage kidney disease, was sent home from the hospital, having recovered enough to be discharged. Sixty-nine genes were edited in the donor pig, including three that coded for a certain sugar found on the surface of pig cells. The edits, hopefully, will make it less likely for the human recipient to reject the transplant.Umair Irfan, senior correspondent at Vox, joins Ira Flatow to talk about the xenotransplantation advance, and how it could affect patients awaiting donor organs. They’ll also talk about other stories from the week in science, including how power grid operators are preparing for the upcoming solar eclipse, NASA’s search for a new lunar rover, an advance in getting robots to make appropriate faces, research into using a drug similar to the obesity medication Ozempic to delay Parkinson’s symptoms, and plans for a new time zone—on the moon.Answering Your Questions About Monday’s EclipseAfter months of excitement, the 2024 total solar eclipse is almost here! On Monday, April 8, the moon will line up perfectly between the Sun and the Earth. For a few short minutes, it’ll plunge parts of North America into total darkness—right in the middle of the day.More than 30 million people live in the path of totality—where the moon will completely block off the sun. It stretches from northwest Mexico, across the US, and into southeastern Canada. Depending how far you are from the path, you might experience a partial eclipse. Magical, nonetheless.Ira talks with Dr. Padi Boyd, astrophysicist at NASA and host of the agency’s podcast Curious Universe, and Mark Breen, meteorologist and planetarium director at the Fairbanks Museum & Planetarium in Vermont. They answer questions our readers and listeners have submitted about the eclipse, and discuss why we should be excited, how to prepare, and what scientists can learn from this phenomenon.For more eclipse-day tips and facts, visit our website.Transcripts for each segment will be available the week after the show airs on sciencefriday.com.
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Covering the outer reaches of space to the tiniest microbes in our bodies, Science Friday is the source for entertaining and educational stories about science, technology, and other cool stuff.
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Folge vom 05.04.2024Recipient Of Pig Kidney Transplant Recovering | Answering Your Questions About April 8 Eclipse
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Folge vom 04.04.2024Our Inevitable Cosmic ApocalypseWhen it comes to the eventual end of our universe, cosmologists have a few classic theories: the Big Crunch, where the universe reverses its expansion and contracts again, setting the stars themselves on fire in the process. Or the Big Rip, where the universe expands forever—but in a fundamentally unstable way that tears matter itself apart. Or it might be heat death, in which matter and energy become equally distributed in a cold, eventless soup.These theories have continued to evolve as we gain new understandings from particle accelerators and astronomical observations. As our understanding of fundamental physics advances, new ideas about the ending are joining the list. Take vacuum decay, a theory that’s been around since the 1970s, but which gained new support when CERN confirmed detection of the Higgs Boson particle. The nice thing about vacuum decay, writes cosmologist Dr. Katie Mack in her book The End of Everything: (Astrophysically Speaking), is that it could happen at any time, and would be almost instantaneous—painless, efficient.The End Of Everything is our SciFri Book Club pick for April—you can join in on the community conversation and maybe even win a free book on our book club page. In this interview from 2020, Mack joins Ira to talk about the diversity of universe-ending theories, and how cosmologists like her think about the big questions, like where the universe started, how it might end, and what happens after it does.Also, Nobel Prize-winning psychologist Dr. Daniel Kahneman died this week at the age of 90. His work turned many traditional ideas about economics upside-down, arguing that people often make bad decisions that go against their own self-interest. It’s something he continued to study throughout his career, and that he wrote about in the 2022 book Noise: A Flaw in Human Judgment. At the end of this segment, we revisit an interview from 2022 with Kahneman in remembrance of his long career studying cognitive biases.Transcripts for each segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
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Folge vom 03.04.2024The Complicated Truths About Offshore Wind And Right WhalesBy the time researchers found the dead whale on a Martha’s Vineyard beach, her jet-black skin was pockmarked by hungry seagulls, her baleen had been dislodged from her mouth, and thin rope was wrapped tightly—as it had been for 17 months—around the most narrow part of her tail.Researchers quickly learned this was a 12-ton, 3-year-old female known as 5120, and that she was a North Atlantic right whale, a species with just about 360 members left.A few weeks later, NOAA Fisheries announced that the entangling rope came from lobster fishing gear set in Maine state waters. The pain and discomfort of the entanglement likely affected 5120’s ability to swim and eat until finally, experts say, exhaustion or starvation probably killed her. A final cause of death is still pending.The death of 5120 was devastating to right whale advocates, who know that losing a female doesn’t just mean losing one whale, but dozens of others that could have come from her future calves. For them, a death is often followed by a period of grief, and a renewed commitment to their work. And that might have been the end of 5120’s story.But then came the online comments. Hundreds, perhaps thousands, across social media blamed offshore wind farms—the noise, electricity generated, and the mere presence of turbines. Along the way, the truth about 5120 became a non-concern.In many cases, the rumors about offshore wind hurting and killing right whales are quite possibly spread from a place of concern, mistrust, or fear by well-meaning people who want to know our oceans are safe for marine mammals. But few people want that more than right whale scientists, who have dedicated their careers to saving a species that appears to be just a few decades from extinction. For many of them, talking about offshore wind has its own challenges, both because of the unknowns that come with a nascent industry and the knee-jerk reactions from people on all sides of the issue. So they say that yes, they’re uneasy about the potential threats of wind farms. But they agonize over the prospect of climate change destroying right whales’ shot at survival via their food web and ecosystem.Read more at sciencefriday.com.Transcripts for each segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
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Folge vom 02.04.2024The Bumpy Road To Approving New Alzheimer’s DrugsIn the past few years pharmaceutical companies have developed a string of new Alzheimer’s drugs called anti-amyloids, which target amyloid plaques in patients’ brains. These plaques are one of the key biomarkers of the disease.The first of these drugs, Aduhelm, was approved by the FDA in 2021 amid enormous controversy. The FDA approved the drug despite little evidence that it actually slowed cognitive decline in patients. Biogen, the maker of Aduhelm, pulled the plug on further research or sales of the drug last month.In January 2023 The FDA approved another anti-amyloid medication from Biogen, lecanemab, sold under the brand name Leqembi. This time, there was much stronger evidence. Clinical trial results showed that the drug showed a modest improvement in cognitive decline in the early phases of the disease. But the drug comes with risks, including brain swelling and bleeding.Most recently, at the beginning of March, the FDA delayed approval of another anti-amyloid drug, donanemab, created by Eli Lilly. The FDA said it will be conducting an additional review to further scrutinize the study design and efficacy data.From the outside looking in, these Alzheimer’s drugs appear to be mired in controversy. How well do they actually work? And why has there been so much back and forth with the FDA?To answer those questions and more, guest host Arielle Duhaime-Ross talks with Dr. Jason Karlawish, professor of medicine, medical ethics and health policy, and neurology at the University of Pennsylvania’s Perelman School of Medicine, and co-director of the Penn Memory Center.Transcripts for each segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.