This week, we've heard from researchers trying to untangle the effects of the "trip" that often comes with psychedelics and ketamine from the ways these drugs might change the human brain. For part three of our series on psychedelic drug research, we get a glimpse into why some researchers are taking the "trip" out of these drugs altogether. You don't need to have heard the previous two episodes to understand this episode on what could be next for psychedelic medicine.Catch the rest of this series on psychedelics and related drugs this week by following us on Spotify and Apple Podcasts. They're the previous two episodes in our podcast feed.Have other questions about psychedelics and the brain? Let us know by emailing shortwave@npr.org! Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy
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New discoveries, everyday mysteries, and the science behind the headlines — in just under 15 minutes. It's science for everyone, using a lot of creativity and a little humor. Join hosts Emily Kwong and Regina Barber for science on a different wavelength.If you're hooked, try Short Wave Plus. Your subscription supports the show and unlocks a sponsor-free feed. Learn more at plus.npr.org/shortwave
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Folge vom 09.04.2025Could Psychedelics Become Tripless?
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Folge vom 08.04.2025What If You Took The "Trip" Out Of Ketamine?What if you could get all the potential benefits of ketamine without the "trip"? For part two of our series on psychedelics, we look at how some researchers are trying to disentangle the "trip" from the drugs' effects on the brain — and why the answer could help direct the future of psychedelic research. (Spoiler alert: People generally know if they're tripping or not.) This episode: a researcher navigating this challenge by putting his patients to sleep. Catch the rest of this series on psychedelics and related drugs this week by following us on Spotify and Apple Podcasts. Have other questions about psychedelics and the brain? Let us know by emailing shortwave@npr.org! Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy
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Folge vom 07.04.2025Why The Trip Complicates Psychedelic ResearchResearchers are studying psychedelics as a possible treatment for conditions like depression, PTSD and substance use disorders. But they don't know exactly how these drugs work. Getting the answer to this question is especially difficult when people often take psychedelics like LSD and psilocybin for the "trip." This week on Short Wave, we're talking to researchers about how they're trying to untangle the effects of this "trip" from the ways psychedelics might change the human brain ... and why the answer could help direct the future of psychedelic research. Catch the rest of this series on psychedelics and related drugs this week by following us on Spotify and Apple Podcasts. Have other questions about psychedelics and the brain? Let us know by emailing shortwave@npr.org! Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy
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Folge vom 04.04.2025Could Running Change Your Brain?Running an entire marathon takes a lot of energy. Neuroscientist Carlos Matute knows this: he's run 18 of them. He wondered how runners' bodies get the energy they need to make it to the finish line. His new research in the journal Nature Metabolism may be the first step in answering the question – and suggests their brains might be (temporarily) depleting a fatty substance that coats nerve cells called myelin. Have other questions about the brain? Let us know by emailing shortwave@npr.org! Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+ at plus.npr.org/shortwave.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy