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Andrew Marr wanders the globe with Paul Theroux, as he celebrates the pleasures and pains of travel, and discovers what makes the best travel writing. The General Secretary of Amnesty International Salil Shetty looks back at 50 years of the organisation, and argues that Amnesty has had to change from a small letter-writing charity aimed at freeing dissidents, to a global multi-national focused on poverty and gender issues. At 50 you're generally considered middle-aged and heading towards retirement, but the journalist Catherine Mayer rejects the traditional patterns of aging, arguing that more and more people are starting to live agelessly. And the landscape artist Charles Jencks explains how science and the patterns inherent in nature have influenced his designs. Producer: Katy Hickman.

Andrew Marr talks to the former British ambassador, Sherard Cowper-Coles, about the failures of Western policy in Afghanistan, and how diplomacy would have been a better option than the gun. In 2003 Baha Mousa was arrested by the British Army in Basra, in Iraq. Two days later he was dead. Richard Norton-Taylor sifts through all the evidence to bring the public inquiry into his death to the stage. David Pryce-Jones asks what motivates those who take up foreign causes, to the detriment of their own country, in Treason of the Heart. And the philosopher Angie Hobbs turns to the Greek Gods to untangle modern ideas of heroism and bravery.Producer: Katy Hickman.

Andrew Marr talks to Francis Fukuyama about the development of political institutions from the early tribal societies to the growth of the modern state. Pakistan has often been referred to as a 'failed state', but Anatol Lieven argues that despite its reputation it has the makings of a modern, viable and coherent country. The author of The Reluctant Fundamentalist, Mohsin Hamid, explores what it means to be middle class in Pakistan, and Tahmima Anam looks back to Bangladesh's fight for Independence, and the relationship between religion and politics in the country of her birth. Producer: Katy Hickman.