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Andrew Marr talks to the science fiction writer China Mieville, whose latest planetary creation explores the links between language and thought, and asks what it means to have no concept of lying. AN Wilson explores a world closer to home, but no less alien, medieval Florence, as he tries to uncover the life and work of Dante. Jonathan Bates' play, Being Shakespeare also attempts to bring to life the work of the Bard and the real man behind the legend, by placing him in his historical context. And the prize-winning poet Jo Shapcott argues for the transformative nature of poetry. Producer: Katy Hickman.

Andrew Marr explores the limits of science and art in this week's Start the Week. The philosopher and neuroscientist Raymond Tallis mounts an all-out assault on those who see neuroscience and evolutionary theory as holding the key to understanding human consciousness and society. While fellow scientist Barbara Sahakian explores the ethical dilemmas which arise when new drugs developed to treat certain conditions are used to enhance performance in the general population. And the gerontologist Aubrey de Grey looks to the future when regenerative medicine prevents the process of aging. Producer: Katy Hickman.

Andrew Marr talks to Tim Harford about the key to success. The 'undercover economist' argues that the fear of failure paradoxically leads to greater and more dangerous failures - from oil disasters to world conflict. Success in parliament is often mercurial, but the new Director of the Institute for Government and former Labour Minister, Andrew Adonis believes the pool of talent for the top jobs is too small, and that Ministers should be better prepared for their role. Priyamvada Gopal argues that university education is becoming one of the country's biggest failures. She believes the humanities have been denigrated, as consecutive governments have emphasised the value of work, over knowledge. And Eli Pariser explores the world of internet personalisation in which your every move is tracked and individual choices assessed: he warns that it's the end of objective news and the free exchange of ideas. Producer: Katy Hickman.