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What can the cosmos tell us about our past and future? Tom Sutcliffe and guests look skyward and deep into the quantum world to ask how much we can really know about the universe - and about ourselves. Space scientist Maggie Aderin-Pocock, presenter of this year’s Royal Institution Christmas Lectures, shares her passion for inspiring the next generation to think big, as she explores the wonders of our solar system and the questions that still puzzle astronomers. Physicist and cosmologist Paul Davies introduces his new book Quantum 2.0, charting the strange and revolutionary principles of quantum mechanics and how they are reshaping technology, science, and our understanding of reality itself. From the Natural History Museum, Caroline Smith brings insights from meteorites — fragments of ancient worlds — and explains how these cosmic messengers help scientists search for life beyond Earth and piece together the story of our solar system’s origins. Together, in Radio 4's weekly ideas discussion programme Start the Week, they consider the limits of knowledge: whether in decoding quantum mysteries, interpreting rocks from space, or imagining the motivations of those who first looked to the stars.Producer: Ruth Watts Assistant Producer: Natalia Fernandez

What can genetics and palmistry tell us about how we understand identity, character and health? Adam Rutherford is joined by Professor of Zoology Matthew Cobb; the historian Professor Alison Bashford and the geneticist Charlotte Houldcroft.Matthew Cobb discusses his biography Crick: A Mind in Motion. From the discovery of DNA’s structure to Francis Crick’s later work on consciousness, Cobb reveals a restless thinker whose collaborations — with scientists, artists and poets — shaped some of the most profound ideas of the 20th century.Alison Bashford turns to palm reading in her new book Decoding the Hand, a history of palmistry and its surprising entanglement with science, medicine and magic.The geneticist Charlotte Houldcroft's research uses ancient DNA to work out how DNA viruses - such as smallpox and herpes - change over time and the consequences of this evolution for our immune systems.Producer: Natalia Fernandez

How can we reclaim the internet? Tom Sutcliffe and guests discuss the digital age - its supporters and discontents. Tech critic Cory Doctorow introduces his new book Enshittification, a blistering diagnosis of how online platforms have decayed — from innovation to exploitation — and what we can do to make it better for ordinary users. Novelist and broadcaster Naomi Alderman draws on history in Don’t Burn Anyone at the Stake Today, arguing that we’ve lived through information crises before, and that lessons from the invention of writing and the printing press can help us navigate today’s digital turbulence. Journalist Oliver Moody, the author of Baltic: The Future of Europe, discusses Estonia’s radical embrace of digital governance, and what it reveals about the possibilities — and limits — of a truly connected state.Producer: Katy Hickman Assistant Producer: Natalia Fernandez