Huberman Lab Folgen

In this episode, my guest is Dr. Mark D'Esposito, M.D., a neurologist and professor of neuroscience and psychology at the University of California, Berkeley. We discuss the brain mechanisms underlying cognition and the forms of memory required for focus, productivity, planning and achieving goals, and learning. We discuss neurochemicals such as dopamine and acetylcholine and how they can be leveraged to improve cognitive functioning. We also discuss concussion, traumatic brain injury (TBI), Alzheimer's, and Parkinson's disease, and ways to restore or slow cognitive decline by using pharmacologic, lifestyle and behavioral protocols. This episode provides a modern understanding of cognition and memory and actionable tools to optimize brain health and function. For show notes, including referenced articles and additional resources, please visit hubermanlab.com. Thank you to our sponsors AG1: https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/hubermanlab Waking Up: https://wakingup.com/huberman Timestamps (00:00:00) Dr. Mark D’Esposito (00:02:08) Sponsors: Maui Nui, Joovv & Eight Sleep (00:06:23) Brain & Frontal Lobes, Prefrontal Cortex, Executive Function (00:10:31) Frontal Lobe Development, Children (00:14:12) Rules, Context & Impulse Control; Learning & Goals (00:21:45) Focus, Improving Executive Function (00:26:04) Connections & Top-Down Signals (00:29:02) Sponsor: AG1 (00:30:29) Frontal Lobe Injury; Emotional Regulation (00:37:26) Smartphones, Social Media (00:44:37) Working Memory, Dopamine (00:52:59) Sponsor: LMNT (00:54:22) Dopamine Levels & Working Memory, Cognitive Tasks, Genetics (01:00:03) Bromocriptine & Working Memory, Dopamine (01:06:21) Guanfacine, Neurotransmitter Levels, Pupil Dilation & Biomarker Tests (01:12:46) Bromocriptine, Olympics; Pharmacology & Cognitive Function, Adderall (01:19:27) Concussion, Traumatic Brain Injury (TBI) (01:25:22) Sleep, TBI, Concussion & Executive Function; BrainHQ (01:31:57) Aging & Frontal Executive System; Brain Health (01:39:26) Tools: Brain Health & Boosting Executive Function, Books (01:47:26) Alzheimer’s Disease, Genetics, Pharmacology (01:51:48) Parkinson’s Disease, L-Dopa; Coping with Alzheimer’s; Nicotine (01:58:37) Estrogen & Dopamine, Cognition; Tool: Physical Exercise (02:04:43) Tool: Mindfulness Meditation & Executive Function (02:10:31) Brain Networks; Modularity (02:17:08) Modularity, Brain Indices (02:22:53) Psilocybin; Transcranial Magnetic Stimulation (02:30:16) Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Momentous, Social Media, Neural Network Newsletter Disclaimer Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode, I discuss the importance of oral health for dental and microbiome health and general physical and mental well-being. I explain science-supported protocols for strengthening your teeth and gums, including how to remineralize your teeth. I cover the best approaches and timing for brushing and flossing, tongue, gum, and oral microbiome care and how oral health is critically important to offset metabolic, cardiac, and brain diseases, including dementia. I also discuss proper nutrition for oral health, fluoride, and how sugar and mouth breathing can accelerate tooth decay. This episode ought to be of interest to everyone seeking to improve their physical health, mental health, and lifespan, given the critical role that oral health plays in all of these. Read the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman LMNT: https://drinklmnt.com/hubermanlab Timestamps 00:00:00 Oral Health   00:03:44 Sponsor: LMNT   00:07:13 Oral Health Quiz   00:13:53 Teeth Biology, Cavity Repair   00:20:01 Mouth, Gums, Saliva   00:23:54 Sponsor: AG1   00:28:51 Cavity Formation, Bacteria, Sugar, Acidity   00:35:10 Teeth Remineralization, Fluoride, Water   00:43:58 Tools: The “Do Nots” of Oral Health, Mouth Breathing   00:54:48 Tools: Fasting & Teeth Remineralization; Nighttime Toothbrushing   01:03:23 Proper Teeth Brushing; Tooth Sensitivity & Gums   01:08:16 Bacteria, Plaque & Tartar; Tooth Polishing   01:11:02 Proper Flossing Technique, Waterpik; Children & Flossing   01:14:23 Tool: Xylitol, Bacteria & Cavity Prevention   01:19:43 Toothpastes: Xylitol, Fluoride, Hydroxyapatite   01:22:38 Mouthwash & Alcohol, Antiseptic Mouthwash   01:26:29 Tools: Baking Soda, Hydrogen Peroxide?, Salt Water Rinse   01:32:36 Alcohol-Based Mouthwash, Nitric Oxide   01:34:52 Tools: Canker Sore Prevention & Gut Microbiome; Sleep   01:37:47 Tools: Tongue Brushing; Toothbrush Care   01:41:38 Teeth Sealants; Metal Fillings, Mercury, Mastic Gum; Root Canals   01:48:43 Dentist Visits, Daily Routines & Oral Health   01:54:17 Practices for Oral Health, Oil Pulling   01:58:21 Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Momentous, Social Media, Neural Network Newsletter   Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode, my guest is Dr. Kay Tye, Ph.D., Professor of Systems Neurobiology at the Salk Institute for Biological Studies and a Howard Hughes Medical Institute (HHMI) Investigator. We discuss the neural circuit basis of social interactions and loneliness. We also discuss how animals and people establish themselves in a group hierarchy by rank and how the brain responds to dominance and subordination. Much of our discussion relates to how social media impacts our sense of social connectedness or lack thereof. The topics covered in this episode are directly relevant to anyone interested in the neuroscience of mental health, work-life balance, abundance versus scarcity mindset, and interpersonal dynamics. Read the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman LMNT: https://drinklmnt.com/hubermanlab Timestamps 00:00:00 Dr. Kay Tye   00:02:56 Sponsors: LMNT   00:06:40 Amygdala; “Valence”   00:12:43 Novelty; Reward & Punishment Response   00:20:06 Amygdala & Hunger; Social Interaction   00:26:21 Social Media & Social Connection; Tool: Email & Time Management   00:31:21 Sponsor: AG1   00:36:30 Social Media; Friction & Feedback, Leadership   00:43:44 Social Isolation, Harlow Experiments, “Loneliness Neurons”   00:51:47 Social Homeostasis, COVID-19 Pandemic & Loneliness   01:01:29 Quality of Social Contact, Social Homeostasis, Social Media   01:09:42 Social Media, Relationships; Social Isolation & Exclusion   01:18:26 Empathy: Friend vs. Foe   01:28:40 Background & Empathy, Diversity, Emotional Regulation   01:34:34 Abundance vs. Scarcity Mindset   01:37:22 Social Rank & Hierarchy, Sibling Order, Development   01:45:54 Dynamic Hierarchy; Dominants vs. Subordinates; Mentors   01:55:32 Psychedelics: Research & Mechanisms; Psilocybin   02:06:28 Work-Life Balance, Fitness & Extracurriculars   02:11:56 Personal Life, Diversity, Happiness; Typical Day   02:15:42 Science & Academia; Future Directions   02:23:48 Research & Science Outreach   02:28:48 Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Momentous, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices