Science Magazine Podcast Folgen

New clinical trials for treatments of an always fatal brain disease, and what happens with pests when a conventional and organic farm are neighbors   First up on this week’s show, a new treatment to stave off prion disease goes into clinical trials. Prions are misfolded proteins that clump together and chew holes in the brain. The misfolding can be switched on in a number of ways—including infection with a misfolded prion protein from an animal or person. Staff Writer Meredith Wadman talks with host Sarah Crespi about new potential treatments—from antisense nucleotides to small molecules that interfere with protein production—for these fatal neurodegenerative diseases.   Next on the show: Freelance producer Katherine Irving talks with Ashley Larsen, associate professor of agricultural and landscape ecology at the University of California, Santa Barbara, about the effects of organic farms on their neighbors. If there are lots of organic growers together, pesticide use goes down but conventional farms tend to use more pesticides when side by side with organic farms.   This week’s episode was produced with help from Podigy.   About the Science Podcast   Authors: Sarah Crespi; Katherine Irving; Meredith Wadman LINKS FOR MP3 META   Episode page: https://www.science.org/doi/10.1126/science.z91m76v Learn more about your ad choices. Visit megaphone.fm/adchoices

Investigating “infantile amnesia,” and how generalized fear after acute stress reflects changes in the brain   This week we have two neuroscience stories. First up, freelance science journalist Sara Reardon looks at why infants’ memories fade. She joins host Sarah Crespi to discuss ongoing experiments that aim to determine when the forgetting stops and why it happens in the first place.   Next on the show, Hui-Quan Li, a senior scientist at Neurocrine Biosciences, talks with Sarah about how the brain encodes generalized fear, a symptom of some anxiety disorders such as social anxiety and post-traumatic stress disorder.   This week’s episode was produced with help from Podigy.   About the Science Podcast   Authors: Sarah Crespi; Kevin McLean; Sara Reardon   Episode page: https://www.science.org/doi/10.1126/science.z9bqkyc Learn more about your ad choices. Visit megaphone.fm/adchoices

What modern Indian genomes say about the region’s deep past, and how vitamin A influences stem cell plasticity First up this week, Online News Editor Michael Price and host Sarah Crespi talk about a large genome sequencing project in India that reveals past migrations in the region and a unique intermixing with Neanderthals in ancient times.   Next on the show, producer Kevin McLean chats with Matthew Tierney, a postdoctoral fellow at Rockefeller University, about how vitamin A and stem cells work together to grow hair and heal wounds.   This week’s episode was produced with help from Podigy.   About the Science Podcast   Authors: Sarah Crespi; Kevin McLean; Michael Price Episode page: https://www.science.org/doi/10.1126/science.zfhqarg   About the Science Podcast: https://www.science.org/content/page/about-science-podcast Learn more about your ad choices. Visit megaphone.fm/adchoices