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Jared Diamond explores how countries survive national crises. The Pulitzer Prize-winning author and polymath talks to Andrew Marr about the process seven countries went through at moments of huge upheaval – from Japan and Finland to Australia and Chile. Using the lessons learnt in overcoming personal trauma, Diamond charts the painful process of self-appraisal, selective change and flexibility needed to move forward.Britain is facing its own national crisis, with the public and political parties divided over Brexit, political leadership and the way to move forward. Professor David Runciman and the Associate Director at the IEA Kate Andrews put Jared Diamond’s thesis to the test. They explore how far we can learn from past disasters and whether there are core national values that could help to unite the country. And, as the Conservative leadership contest begins and President Trump arrives in the UK, they discuss the limits to power and the myth of the strong leader.

In a special edition recorded live at the Hay Festival, Tom Sutcliffe discusses the impact of human ingenuity. From the myth of Frankenstein to geoengineering, he explores how normality and deviancy became entrenched in society. In her latest novel, the award-winning writer Jeanette Winterson moves between 1816, when the young Mary Shelley wrote the great Gothic novel of scientific hubris, Frankenstein, and the present day, exploring the far-reaching consequences of the AI revolution. John Browne, the former CEO of BP, argues against putting the brakes on technological advance. He maintains that civilisation is founded on engineering innovation.Naomi Wolf looks back to the 1857 Obscene Publications Act to pinpoint the moment that law enforced the sexuality morality of the time. She sees reverberations lasting to this day.Producer: Katy Hickman

Dr Joshua Mezrich is a leading transplant surgeon. He tells Andrew Marr how death and life are intimately connected in his field of expertise. And he explains the extraordinary breakthroughs that have emerged in transplant surgery, along with the ethical questions that arise when choosing who will be given the chance of a new beginning. Scientific research needs to be evidence-based. But it can too easily be based on underlying assumptions and biases. The science writer Angela Saini reports on the history - and recent revival - of race science, a field of study that sees race as a biological fact.Caroline Criado Perez exposes the gender biases in medical and scientific research. She argues that women have often been excluded from the data which has had a huge impact on the efficacy of the pills prescribed, and the treatment offered.The latest promise of better healthcare is personalised medicine, which aims to get the right dose to the right patient at the right time. But Richard Ashcroft, Professor of Biomedical Ethics, cautions that grouping patients by their genetic constitution may well create new forms of inequality.Producer: Katy Hickman