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Huberman Lab

The Huberman Lab podcast is hosted by Andrew Huberman, Ph.D., a neuroscientist and tenured professor in the department of neurobiology, and by courtesy, psychiatry and behavioral sciences at Stanford School of Medicine. The podcast discusses neuroscience and science-based tools, including how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health, as well as existing and emerging tools for measuring and changing how our nervous system works. Huberman has made numerous significant contributions to the fields of brain development, brain function, and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills, and cognitive functioning. He is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award, given to the scientist making the most significant discoveries in the study of vision, in 2017.  Work from the Huberman Laboratory at Stanford School of Medicine has been published in top journals, including Nature, Science, and Cell, and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets. In 2021, Dr. Huberman launched the Huberman Lab podcast. The podcast is frequently ranked in the top 10 of all podcasts globally and is often ranked #1 in the categories of Science, Education, and Health & Fitness.

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Folgen von Huberman Lab

252 Folgen
  • Folge vom 10.05.2021
    Supercharge Exercise Performance & Recovery with Cooling
    This episode I explain the science of heating and cooling the body, a process called thermoregulation-- and how to apply that knowledge to significantly improve physical performance. I describe the three areas of our body that can remove heat (or bring heat into the body) faster than anywhere else, why that is so, and how proper cooling of these areas with specific protocols can allow people to perform 200-600% more volume and repetitions of resistance exercises at the same weight loads, or to run, cycle or swim significantly further. I also describe how to use directed cooling of so-called glabrous skin: the bottoms of feet, palms and face, to significantly enhance recovery times from exercise. Also, why the common practices of trying to heat up or cool the body via the torso or whole-body submersion in cold can be inefficient and/or dangerous-- and the better alternatives. Finally, I discuss the temperature-effects of caffeine, alcohol and anti-inflammatory compounds. The information in this episode is focused on mechanisms and tools for increasing athletic or exercise performance. For the full show notes, visit hubermanlab.com. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Timestamps (00:00:00) Introduction (00:00:31) Sponsors: AG1, LMNT (00:05:08) Physical Performance & Skill Learning (00:06:40) Optimal Learning Protocol (Recap): 4 Steps (00:08:31) Variables Impacting Physical Performance (00:10:00) Temperature Is the Dominant Variable (00:12:08) Understanding Mechanism Is Key (00:13:42) Heat: The Enemy of All Performance (& Why) (00:16:30) Blood Flow & Sweating & Piloerection (00:22:35) Heat Is What Limits Effort: Even If You Feel Fine/Motivated (00:25:29) Proper Cooling Can Double, Triple, Quadruple (Or More) Your Ability (00:26:42) Heat Induced Confusion & Death (00:30:02) The Three Body Parts Best For Heating & Cooling Your Whole Body (00:31:38) Face, Palms, Bottoms of Feet; Glabrous Skin (00:33:00) Arterio-Venous Anastamoses (AVAs) Are Super Cool(ing)! (00:37:15) Palmar Cooling Can Supercharge Your Athletic Performance (00:38:35) ATP, Pyruvate Kinase & Heat (00:40:55) Palmer Cooling Outperforms Anabolic Steroids Several-Fold (00:43:45) Increasing Endurance, Willpower & Persistence (00:46:33) Cardiac Drift, & Moving the ”I Quit” Point (00:50:44) Deliberate Heating: Myths and Better Protocols (00:53:20) Protocols For Self-Directed Cooling To Vastly Improve Performance (00:59:23) How To Use Cold To Recover Faster & More Thoroughly (01:02:05) Ice Baths & Cold Showers Can Prevent Training Progress: mTOR, etc. (01:06:29) Alcohol, Caffeine, NSAIDs: Their Temperature Effects Matter (01:09:44) Are Stimulants Counter Productive For Performance? It Depends. (01:12:00) The Caffeine Rule & “Caffeine Adaptation” (01:14:20) NSAIDs for Training: Performance Enhancements & Risks (01:17:00) The Best Way to Explore Your Own “Parameter Space” (01:18:35) Tools: How To Try (01:21:35) Cost-Free Support, & Additional Support & Resources Title Card Photo Credit: Mike Blabac Disclaimer
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  • Folge vom 03.05.2021
    Boost Your Energy & Immune System with Cortisol & Adrenaline
    This episode I describe the biology of two essential hormones we all make: cortisol and adrenaline (also called epinephrine). Cortisol and adrenaline powerfully regulate our levels of energy, focus and immune system function. I describe various science-supported tools and practices to increase or decrease cortisol and/or adrenaline, depending on one's specific needs and goals. I also describe the biology of nootropics, and how cortisol and adrenaline can improve or degrade learning. Finally, I review the scientific data and tools for timing the release of these hormones to improve memory, energy and immune system function. Access the full show notes, including referenced articles, resources and more at hubermanlab.com. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/huberman Waking Up: https://www.wakingup.com/huberman Momentous: https://www.livemomentous.com/huberman Timestamps (00:00:00) Introduction (00:00:31) Sponsors: AG1, LMNT & Waking Up (00:05:41) Energy & Your Immune System, & Learning Faster (00:08:34) Why & How Intermittent Fasting Increases Growth Hormone (00:11:56) Why Your Stomach Growls (00:13:09) Hot Baths & Hormones (00:14:35) Energy, Adrenaline (Epinephrine), & Cortisol (00:15:48) Cortisol & Cholesterol, Competition With Testosterone & Estrogen (00:17:54) Adrenaline (Epinephrine) Is Your (Immune Systems) Best Friend (00:18:48) Cortisol Basics In Two (Actually 1) Minute/s (00:19:48) Adrenaline Basics In Two Minutes (00:21:32) Tool: Time Your Cortisol Peak To Waking Using Specific Light Intensities (00:27:20) Brief Increases In Cortisol & Adrenaline Boost Energy, Focus & Immunity (00:30:04) Ways To Increase Adrenaline, Epinephrine & Cortisol & Why That Is Good (00:35:00) Does Mindset During Stress Matter? (00:36:15) Protocols: Adrenaline Breathing Described (00:39:00) Practices To Increase Energy Without Increasing Stress (00:45:00) Using Stressors to ENHANCE Our Immune System: Science & Tools (00:55:11) Timing Thyroid Release For Energy (00:57:02) Adrenaline/Stress Increase Performance & Memory. IF They Are After Learning (01:02:45) An Optimal Learning Protocol (01:03:20) Coffee Changes Your Brain & Increases Connectivity Of “Anxiety Circuits” (01:05:43) Nootropics: Two Kinds, & How & Why They Work, “Neural Energy” (01:09:00) Biology of Comfort Foods: From Negative to Positive Feedback Loops (01:14:00) Bombesin: Energy Without Eating (01:15:00) How Stress Makes Our Hair Gray, & How To Prevent Stress-Induced-Graying (01:18:05) Blunting Chronic Cortisol, Including: Ashwagandha & Science Of (01:25:50) Licorice Increases Cortisol & Blood Pressure, & Reduces Testosterone (by Glycyrrhizin) (01:28:50) Apigenin: Anti-Cortisol (01:29:53) Protocols For Optimizing Energy & Immune System Function (& Learning) (01:37:00) When Fasting, Exercise, Cold & Intense Breathing Become Detrimental (01:39:00) Prescription Compounds (01:39:47) Tools For Accessing Alert & Calm States of “Energy”: Separating The Brain & Body (01:42:11) Ways To Apply Knowledge Presented Today (01:43:20) No-Cost Ways To Support Us, Feedback, Sponsors, Patreon, Partners, “Office Hours” Title Card Photo Credit: Mike Blabac Disclaimer
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  • Folge vom 26.04.2021
    How to Control Your Metabolism by Thyroid & Growth Hormone
    This episode discusses metabolism and how our thyroid hormone and growth hormone control our metabolism. I also clarify that metabolism isn't just about burning energy, it’s about converting energy from different sources into fuels for building and repairing our tissues such as muscle, brain, and tendons and mobilizing energy from body fat storage. I discuss the role of iodine, selenium, and salt for thyroid health, and how specific exercise protocols, amino acids and temperature can dramatically shift levels of growth hormone release in waking and in sleep. I also describe the current landscape of prescription compounds, peptides and other factors for changing levels of thyroid and growth hormone, and some of their risks. Throughout the episode, mechanisms and tools grounded in specific mechanisms are discussed. Supplements from Thorne https://www.thorne.com/u/huberman Timestamps (00:00:00) Introduction (00:06:05) Thyroid & Growth Hormone (00:08:44) Food Shapes: Do They Matter? (00:11:43) Stevia: Naming & Impact (00:13:30) Metabolism 101: Your Brain the Furnace (00:17:33) Releasing Hormones From Your Brain, Stimulating Hormones from Your Pituitary (00:21:04) Thyroid Hormone’s Real Effects: Growth, Repair and Energy Consumption of Tissues (00:22:45) Iodine, L-Tyrosine & Selenium: The Trio Essential For Thyroid Function (00:26:05) How Much Iodine Do We Need? By Food, Supplement or Ocean Air (00:28:09) Selenium For Thyroid: Brazil Nuts & Other Valuable Sources (00:33:05) Selenium For Pregnancy, Prostate Cancer Risk, Acne (00:35:20) “Clean Eating” Downsides: Cruciferous Vegetables, Leeching Iodine (00:39:00) Other Benefits of Iodine: Reducing Inflammation (00:41:00) Why & How Increased Thyroid Increases Metabolism (00:42:12) What To Eat To Support Your Brain (00:43:00) Hyperthyroidism (Too Much) & Hypothyroidism (Too Little) (00:44:35) Menstruation: Thyroid Carbohydrate & Sugar Craving (00:45:33) Ketogenic Diet & Its Effects On Thyroid, Rebound Weight Gain (00:48:39) Growth Hormone: What, Why & How (00:51:18) Growth Hormone (GH) Changes Across The Lifespan & Risks of GH Therapy (00:53:40) How To Powerfully Increase Growth Hormone: Know The Natural Triggers (00:54:49) Not Eating Within 2hrs of Sleep: Keep Blood Glucose Low(ish) At Sleep (00:55:43) Delta Wave Brain Activity Is the Trigger For Growth Hormone Release (00:58:25) LOW Doses of Melatonin Supplementation For Increasing GH Release (01:01:00) Book: Altered Traits, Binaural Beats? Delta Waves Access (01:04:35) Specific Types & Duration of Exercise That Stimulate Growth Hormone & Warmups (01:08:40) Keeping Low Blood Glucose & Ensuring A Cool Down For Two Phase GH Release (01:10:36) Sex Differences For WHEN During Exercise Growth Hormone and IGF-1 Release Occurs: Males Have To Last Longer (01:14:10) Supplements That Increase Growth Hormone 100-400% (or more): Arginine, Ornithine (01:18:20) Arginine & Exercise Together Can Be Counter-Productive (01:19:50) L-Citrulline Better For Arginine Than Arginine Itself (?!); & Blood Pressure Caution (01:23:09) Growth Hormone Changes Across The Lifespan: No One Escapes (01:26:00) Heat (& Cold) for Triggering Extremely Large Increases In Growth Hormone (01:29:20) Specific Heat Protocols For Increasing Growth Hormone: Up To 16-Fold (?!) (01:34:30) 2021 (New) Study: Heat Increases GH, & Lowers Cortisol, No Effects On Testosterone, DHEA Or Prolactin (01:36:00) Prescription Growth Hormone, & Emerging Peptides Therapeutics, Secretagogues Etc. (01:42:25) Synthesis, Summary Of Actionable Steps For Increasing GH and Thyroid Hormone (01:44:00) Zero Cost & Other Ways to Support Our Podcast; & Thank You!
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  • Folge vom 19.04.2021
    How Hormones Control Hunger, Eating & Satiety
    This episode I discuss how hormones from our gut, liver, pancreas and brain control our appetite--and the specific tools we can use to adjust those hormones in order to achieve specific goals. I explain the brain areas that control our desire to eat, and our desire to stop eating. I discuss a hormone we all can make that is regulated by UV-rays from sunlight that reduces our appetite. I also explain that when we eat controls our appetite and not the other way around (and how to leverage that fact). I describe how we are basically always eating until we reach a threshold level of fatty acids and amino acids in our gut and the factors that can alter that signaling and make us eat far more than we need. I also explain how insulin, glucose and glucagon work, why cholesterol is so key for ovary, adrenal, liver and testes function and how the ketogenic diet impacts glucose and thyroid levels. As always, I describe many tools: specific supplements, prescription compounds, specific types (and timing) of exercise to regulate hormones, specific timing and types of eating, ways to reduce sugar cravings by triggering release of the hormone CCK, and more. Note: A future episode will cover Thyroid hormone. Also, I mis-spoke when explaining POMC neurons. I said “P-M-O-C” but should have said “POMC”. Apologies. The name I gave for what POMC is, however, was correct: "proopiomelanocortin". Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Supplements from Thorne https://www.thorne.com/u/huberman Timestamps (00:00:00) Introduction (00:06:59) Hunger: Neural & Hormonal Control (00:08:32) Chewing & Hunger (00:11:05) Siamese Rats Reveal the Importance of Hormones In Hunger (00:13:08) Neurons That Powerfully Control Hunger by Releasing Specific Hormones (00:16:28) Anorexia & Extreme Overeating (00:16:57) Why Sunlight Suppresses Hunger: a-Melanocyte Stimulating Hormone (a -MSH) (00:20:03) Blue-blockers, Injecting a-MSH: Instant Tan & Priapism (00:22:30) Ghrelin: A Hormone That Determines When You Get Hungry, & That You Can Control (00:24:40) Meal Timing Determines Hunger, Not the Other Way Around (00:27:20) Satchin Panda, Circadian Eating & Intermittent(ish) Fasting (00:29:35) How To Rationally Adjust Meal Schedules: The 45min Per Day Rule (00:33:02) CCK (Cholecystokinin): A Hormone In Your Gut That Says “No Mas!” (00:34:55) Eating For Amino Acids, Fatty Acids & Sugar (00:39:05) L-Glutamine: Stimulates the Immune System & Reduces Sugar Cravings (00:43:42) Things To Avoid: Emulsifiers; Alter Gut Mucosa & Nutrient Sensing (00:49:32) “A Calorie Is NOT A Calorie” After All (00:52:36) Insulin & Glucose: Hyperglycemia, Euglycemia, & Hypogylcemia (00:56:12) The Order Your Eat Foods Matters: Managing Your Blood Glucose & Glucagon (01:02:40) Movement, Exercise & GLUT-4 (01:04:50) Why Sugar Stimulates Your Appetite (01:05:40) Keeping Blood Sugar Stable With Specific Exercises, The Power Of Insulin Sensitivity (01:07:55) High-Intensity Exercise, Glycogen & Metabolism (01:10:28) Cholesterol, HDL, LDL & Glucose Management: Ovaries, Testes, Liver, Adrenals (01:15:00) Prescription Compounds That Reduce Blood Glucose: Metformin (01:16:45) Berberine: A Potent Glucose Buffer That Also Adjusts Cholesterol Levels, Canker Sores (01:22:05) Chromium, L-Carnitine, Ginseng, Caffeine, Magnesium, Stevia, Vitamin B3, & Zinc (01:24:34) Acids: Vinegar, Lemons & Limes & False Alkalinity (01:26:40) Ketogenic Diets (In Brief): Effects On Blood Glucose, Thyroid Hormones (01:28:10) Diabetes, Filtering Blood, Sweet Urine (01:31:08) The Power of GLP-1 & Yerba Mate For Controlling Appetite, Electrolytes (01:35:19) Summary & Notes About Thyroid, Estrogen, Testosterone (01:37:20) Zero Cost & Sponsor-Based Ways To Support The Huberman Lab Podcast
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